This comprehensive report is designed to help current suppliers and potential market entrants identify and evaluate emerging opportunities in the Spanish molecular blood banking market during the next five years, and assist industry executives in developing effective business, new product development and marketing strategies.

The report explores future marketing and technological trends in Spain; provides test volume and sales forecasts by market segment/test location; compares features of major automated and semi-automated analyzers; profiles leading and emerging competitors; and identifies specific product and market opportunities facing suppliers during the next five years.

Blood Group Genotyping

PCR, PCR-RFLP, AS-PCR or PCR-SSP, Multiplex PCR, Real Time PCR, Sanger DNA Sequencing, Pyrosequencing

Microarrays

BeadChip Array, BloodChip, Genome Lab SNP Stream, Fluidic Microarray Systems, TaqMan OpenArray, MALDI-TOF-MS, Mini-Sequencing

Blood Typing and Grouping Tests

ABO, Antibody Panels, Antibody Screening/Indirect Antiglobulin, Antigen Typing (C, c, Duffy, E, e, I, i, Kell, Kidd, Le a, b, MN, P, S, s), Antiglobulin (Direct, C3 + IgG, IgG, C3), Crossmatching (Immediate Spin, Full Crossmatch), Rh (D, Du).

Infectious Disease Screening Tests

AIDS (HIV NAT, HIV-1/2), Cytomegalovirus, Hepatitis (HAV NAT, HBV NAT, HBs Ag, Anti-HBc, HCV NAT, HCV, ALT/SGPT), HTLV-I/II, Parvovirus B19 NAT, Syphilis, West Nile Virus NAT

Sales and Market Share Analysis

Sales and market share estimates for leading suppliers of blood banking products by individual product.

Competitive Assessments

Strategic assessments of major suppliers and emerging market entrants, including their sales, product portfolios, marketing tactics, and new products in R&D.

Market Segmentation Analysis

– Comprehensive market segmentation analysis, including review of the market dynamics, trends, structure, size, growth, and key suppliers.

– Test volume and sales forecasts for over 40 blood typing, grouping and infectious disease screening tests, including NAT, by market segment:

– Blood Centers – Hospitals – Commercial/Private Laboratories

Current and Emerging Products

– Analysis of current and emerging blood typing, grouping and infectious disease screening tests.

– Review of automated and semi-automated analyzers.

Technology Review

– Assessment of current and emerging technologies, and their potential applications for the blood banking market.

– Comprehensive lists of companies developing or marketing new technologies and products, by test.

Strategic Recommendations

– New product development opportunities with significant market appeal.

– Alternative market penetration strategies.

– Potential market entry barriers and risks

Table of Contents

I. Introduction
II. Worldwide Technology and Market Overview
A. Major Blood Typing, Grouping and Infectious Disease Screening Tests
1. Blood Typing and Grouping Tests
a. ABO
b. Antibody Panels
c. Antibody Screening
d. Antigen Typing
e. Antiglobulin Test
f. Crossmatch
g. HLA Typing
h. Rh
i. Other Blood Groups
2. Blood Group Genotyping
a. PCR
b. PCR-RFLP
c. AS-PCR or PCR-SSP
d. Multiplex PCR
e. Real Time PCR
f. Sanger DNA Sequencing
g. Pyrosequencing
b. Microarrays
- BeadChip Array
- BloodChip
- Genome Lab SNP Stream
- Fluidic Microarray Systems
- TaqMan OpenArray
- MALDI-TOF-MS
- Mini-Sequencing
3. Infectious Disease Screening Tests
a. AIDS
- Structure and Composition
- Classification
- Origin of AIDS
- Animal Lentivirus Systems
- Virus Receptors
- HIV Infections in Humans
-Pathogenesis & Pathology
-Overview of Course of HIV Infection
- CD4T Lymphocytes and Memory Cells
- Monocytes and Macrophages
- Lymphoid Organs
- Neural Cells
- Viral Coinfections
-Clinical Findings
- Plasma Viral Load
- Pediactric AIDS
-Neurologic Disease
-Opportunistic Infections
-Protozoa
-Fungi
-Bacteria
- Viruses
- Cancer
- Immunity
- Laboratory Diagnosis
-Virus Isolation
-Serology
-Detection of Viral Nucleic Acid or Antigens
- Epidemiology
-Worldwide Spread of AIDS
-United States
-Routes of Transmission
- Prevention, Treatment, And Control
-Antiviral Drugs
-Vaccines Against HIV
- Transmission of HIV in Blood Products
- HIV Transmission in Transplant and Artificial Insemination Recipients
- Diagnostic Tests
- Enzyme Immunoassay Interpretation
- Specificity, Sensitivity, and Predictive Value of Enzyme Immunoassay
- Competition Assays
- Western Blot Technique
- Immuno-Fluorescence Assay (IFA)
- Radioimmunoprecipitation
- HIV-1/HIV-2 Combination Testing
- Methods of HIV-Antigen Detection
- Antigen Assays and Blood Screening
- Urine Tests
- DNA Probes
- Overview
- Quantitative Polymerase Chain Reaction
- In Situ PCR
- Needed Improvements
- Viral Load/Drug Resistance Testing
- Genotype and Phenotype Testing
- Blood Banking Considerations
b. Hepatitis
- Hepatitis A
- Hepatitis B
-Structure and Composition
-Replication of Hepatitis B Virus
- Hepatitis C
- Hepatitis D (Delta Hepatitis)
- Hepatitis E
- Hepatitis G
- Hepatitis Virus Infections In Humans
-Pathology
- Clinical Findings
- Laboratory Features
-Hepatitis A
-Hepatitis B
-Hepatitis C
-Hepatitis D
-Hepatitis E
- Virus-Host Immune Reactions
- Epidemiology
-Hepatitis A
-Hepatitis B
-Hepatitis C
-Hepatitis D (Delta Agent)
- Vaccines and Drugs
c. Cytomegalovirus
- Background
- Chorioretinitis
- Gastrointestinal
- Central Nervous System Disease
- Diagnostic Tests
- Vaccines and Drugs
d. Syphilis
- Background
- Diagnostic Tests
- Vaccines and Drugs
e. West Nile Virus
- Background
- Clinical Syndromes
- Diagnostic Tests
- Vaccines and Drugs
f. Parvovirus B19
- Microbiology
- Epidemiology
- Clinical Syndromes
-Erythema Infectiosum Slapped (cheek)
-Adult Polyarthropathy
-Transient Aplastic Crisis
-Transient Pancytopenia
-Red Cell Aplasia in the Immunocompromised
-Perinatal Infections
- Diagnosis
- Treatment
g. Creutzfeldt-Jakob's Disease
- Background
- Transmission
- Diagnostic Tests
- Major Commercial and Academic Players
-Bayer
-Disease Sciences/BioTec Global
-Imperial College School of Medicine
-Ortho-Clinical Diagnostics
-Pall
-ProMetic Life Sciences
-Proteome Sciences/Idexx
-Q-One Biotech
-Serono
-U.S. Agricultural Research Service
- Drugs
- Vaccines
h. Malaria
i. Chagas Disease
j. Babesiosis
4. Pathogen Reduction
5. Leukocyte Reduction
- Background
- Methods
B. Instrumentation Review: Operating Characteristics, Features and Selling Prices of Leading Automated and Semiautomated Analyzers Manufactured by:
- Abbott
- Beckman Coulter/Danaher
- Becton Dickinson
- Bio-Rad
- BioMerieux
- Cepheid
- Curtis Unyvero
- Gen-Probe/Hologic
- GenMark
- Grifols
- HTG
- Immucor
- Life Technologies
- Nanosphere
- Ortho-Clinical Diagnostics
- Qiagen
- Roche
- Sarstedt
- Siemens
- Tecan
C. Major in Vitro Diagnostic Technologies and Their Potential Applications
1. Molecular Diagnostics
a. Overview
b. NAT
2. Monoclonal and Polyclonal Antibodies
3. Immunoassays
a. Technological Principle
b. Chemiluminescence
c. Enzyme Immunoassays (EIA)
- Overview
- ELISA
- EMIT
- Electrochemical
d. Radioimmunoassays (RIA)
e. Immunoprecipitation
f. Affinity Chromatography
4. Microtitration Plates
5. IT and Automation
6. Lasers
7. Robotics
8. Synthetic Red Cell Substitutes
9. Genetically Engineered Blood Components
a. Albumin
b. Factor VIII
c. Alpha-2 Antiplasmin
d. Antithrombin III
e. Factor IX
f. Von Willebrand's Factor
g. Fibrinogen
h. t-PA
10. Blood Preservation
11. Autologous Blood Transfusion/Freezing
III. Spain
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Supplier Sales and Market Shares for Blood Typing, Grouping and Infectious Disease Screening Tests
IV. Major Product Development Opportunities
A. Molecular Blood Typing and Grouping
B. Infectious Disease Screening
C. Auxiliary
V. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
VI. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
VII. Competitive Assessments
- Abbott
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- BioMerieux
- Bio-Rad
- CellMark Forensics/LabCorp
- Diagast
- DiaSorin
- Fujirebio
- Hologic/Gen-Probe
- Grifols
- Immucor
- Ortho-Clinical Diagnostics
- Proteome Sciences
- Quest Diagnostics
- Quidel
- Roche
- Siemens
- Tecan
- Thermo Fisher

List of Tables

Major Companies Developing or Marketing Blood Typing and Grouping Tests
Major Companies Developing or Marketing HLA Typing Tests
Major Companies Developing or Marketing AIDS Tests
Major Companies Developing or Marketing Hepatitis Tests
Major Companies Developing or Marketing CMV Tests
Major Companies Developing or Marketing Syphilis Tests
Major Companies Developing or Marketing Blood Bank Analyzers
Executive Summary Table: Spain, Total Blood Bank Test Volume and Reagent Sales Forecast By Test Category
Spain, Facilities Performing Blood Bank Tests by Market Segment
Spain, Hospital Laboratories Performing Blood Bank Tests by Bed Size
Spain, Commercial/Private Laboratories Performing Blood Bank Tests By Annual Test Volume
Spain, All Market Segments Blood Typing and Grouping Test Volume Forecast by Market Segment
Spain, All Market Segments Blood Typing and Grouping Test Volume Forecast
Spain, Hospital Laboratories Blood Typing and Grouping Test Volume Forecast
Spain, Blood Banks Blood Typing and Grouping Test Volume Forecast
Spain, Commercial/Private Laboratories Blood Typing and Grouping Test Volume Forecast
Spain, All Market Segments Infectious Disease Screening Test Volume Forecast By Market Segment
Spain, All Market Segments Infectious Disease Screening Test Volume Forecast
Spain, Blood Banks Infectious Disease Screening Test Volume Forecast
Spain, Commercial/Private Laboratories Infectious Disease Screening Test Volume Forecast
Spain, Hospital Laboratories Infectious Disease Screening Test Volume Forecast
Spain, All Market Segments Blood Typing and Grouping Reagent Market Forecast By Market Segment
Spain, All Market Segments Blood Typing and Grouping Reagent Market Forecast By Major Test
Spain, Hospital Laboratories Blood Typing and Grouping Reagent Market Forecast By Major Test
Spain, Blood Banks Blood Typing and Grouping Reagent Market By Major Test Forecast
Spain, Commercial/Private Laboratories Blood Typing and Grouping Reagent Market Forecast By Major Test
Spain, All Market Segments Infectious Disease Screening Reagent Market Forecast by Market Segment
Spain, All Market Segments Infectious Disease Screening Reagent Market Forecast by Test
Spain, Blood Banks Infectious Disease Screening Reagent Market Forecast by Test
Spain, Commercial/Private Laboratories Infectious Disease Screening Reagent Market Forecast By Test
Spain, Hospital Laboratories Infectious Disease Screening Reagent Market Forecast by Test
Spain, Major Suppliers of Blood Typing and Grouping Reagents Estimated Sales and Market Shares
Spain, HIV-1/2 Blood Screening Market, Reagent Sales by Major Supplier
Spain, Hepatitis Blood Screening Market, Reagent Sales by Major Supplier
Spain, HIV/Hepatitis NAT Market, Reagent Sales by Major Supplier
Spain, CMV Blood Screening Market, Reagent Sales by Major Supplier
Spain, Syphilis Blood Screening Market, Reagent Sales by Major Supplier